Abstract
Since the introduction of postpartal and prepartal Anti-D-prophylaxis (Bowman et al., 1978; Thornton et al., 1989), the rate of sensibilisation to the rhesus system has decreased in Germany from 1:20.000 before prophylaxis to 1:1.000 today (Maas et al., 1991). There is, however, little chance that the future could hold an even lower incidence of infants with isoimmunisation caused by Rhesus incompatibility, since prophylaxis has a constant failure rate. In addition, there are other types of isoimmunisations caused by other blood groups, especially anti-c, Kell and Duffy, where no prophylaxis is yet possible. Therefore exchange transfusion (ET) will continue to be a part of the postnatal management in neonates suffering from Morbus haemolyticus.
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