Abstract

Cavitation bubbles can accelerate high-intensity focused ultrasound (HIFU) treatments thermally, chemically, and mechanically. Acoustic generation of cavitation bubbles requires extremely high-intensity or long duration time enough to form a standing-wave field. We have proposed and investigated the ultrasound sequence of a high-intensity short pulse, named as trigger pulse, followed by a relatively lower intensity and longer duration burst, named as heating burst, mainly for the cavitation-enhanced ultrasonic heating. Trigger pulses are used to generate cavitation bubbles then form cavitation clouds. The acoustic power of trigger pulses is more than hundreds of W and the duration is less than 100 μs to avoid effects of standing-wave components. Cavitation bubbles induced by trigger pulses continuously oscillate with heating bursts. The sequence was repeated 3—15 s. Cavitation clouds formation by trigger pulses was observed with a high-speed camera. The temperature measured by thermocouple and tissue coag...

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