Abstract
Brain treatment with High Intensity Focused Ultrasound (HIFU) can be achieved by multichannel arrays through the skull using time‐reversal focusing. Such a method requires a reference signal either sent by a real source embedded in brain tissues or computed from a virtual source, using the acoustic properties of the skull deduced from CT images. This noninvasive computational method allows precise focusing, but is time consuming and suffers from unavoidable modeling errors which reduce the accessible acoustic pressure at the focus in comparison with real experimental time‐reversal using an implanted hydrophone. Ex vivo simulations with a half skull immersed in a water tank allow us to reach at low amplitude levels a pressure ratio of 83% of the reference pressure (real time reversal) at 1MHz. Using this method to transcranially focus a pulse signal in an agar gel (model for in vivo bubble formation), we induced a cavitation bubble that generated an ultrasonic wave received by the array. Selecting the 1MHz...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
