Abstract
This case concerns a 47-year-old woman who was initially diagnosed as having primary hypothyroidism nearly four years prior to this incident; on treatment with levothyroxine sodium (LT4) 150 mg daily. Despite reasonable doses of LT4, and being fully compliant with her therapy, at no stage was her TSH less than 20 mU/L (Table 1). Malabsorption was ruled out and there were no clinical features to suggest this. When the patient was reviewed in the endocrine clinic, she was advised to take the tablets on an empty stomach (rather than with the white tea and breakfast that she had regularly been having immediately following her LT4 tablets). On subsequent follow-up four months later, the TFTs had improved on the same dose of LT4 and she had lost nearly 2 kg in weight despite the ‘Christmas Effect’, as she described it, and she felt well in herself. Subsequent TFTs continue to remain in the reference range with the altered timing of intake of LT4.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
