Abstract
Rapid changes in national rates, with little evidence of cohort effects, must substantially reflect changes in incidence rates due to socioeconomic and behavioral influences, operating with a rather short incubation period. Every newly-rich society usually experiences its epidemic of coronary heart disease. Rate changes for men and women are correlated, but the regression is asymmetrical: greater falls in women seem to reflect some rather uniform widespread sex-specific change, on top of which is another and highly variable factor common to both sexes. Trends are correlated with diet (especially with the constitution of fats). A correlation with stroke trends suggests a common link with population changes in blood pressure, in which obesity may play a part. Other important influences on population trends and differences remain unidentified or unconfirmed.
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