Abstract
gastroenteritis. Fujita et al. suspected that there may be an association between renal hypouricemia and uric acid stone formation in patients with HRV-associated gastroenteritis due to the number of cases, including our own, that have been reported, primarily in Japan (2-6). Urate urolithiasis is rarely seen in children. It is generally associated with an increased urinary concentration of urate and its subsequent deposition. Hyperuricuria and uric acid nephrolithiasis are mainly caused by the increased excretion or disturbed reabsorption of uric acid by the renal proximal tubular cells: the former is accompanied with hyperurice- mia, while the latter may be associated with hypouricemia. Hyperuricemia is observed in children with tumor lysis syndrome, Lesch-Nyhan syndrome and hypoxanthine-
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