Abstract

Stereotactic deep brain stimulation (DBS) of the thalamus and the subthalamic region has been shown to be effective in treating medically refractory tremor over the past few decades. In this article we discuss the merits and drawbacks of stimulating each of the targets in this region, in particular the caudal zona incerta nucleus (cZI). We discuss our recent work in this field and the rationale behind choosing this nucleus to implant bilateral DBS leads for all forms of tremor.

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