Abstract
Up to 25% of hospitalized patients undergo urinary catheterization 1. Indwelling urinary catheters are well recognized as an important cause of nosocomial infections 2. Bacteriuria can be proved in at least 10-15% of such patients, even though a large part of the infections elapses asymptomatic and get benefit from the removal of the device. Nevertheless, up to 4% of patients may develop catheter-related bacteraemia, usually supported by Gram-negative bacteria 3-6. An empirical antibiotic treatment is often started when catheter associated urinary tract infection (CAUTI) is suspected. The uropathogens most frequently involved are Escherichia coli, Proteus spp, Pseudomonas spp, KES (Klebsiella Enterobacter Serratia) group, Staphylococcus spp, Enterococcus spp and Candida spp and they usually show a marked resistance to antimicrobials, if compared to uropathogens not isolated in nosocomial infections. Such resistance may be increased by an inappropriate antibiotic treatment. The spectrum of uropathogens may change over time and their patterns of antimicrobial susceptibility may be influenced by the policy of antibiotic use in some clinical settings. This study was undertaken to evaluate some risk factors which may affect the isolation rates of uropathogens and their in vitro antibiotic resistance in patients with CAUTI in a teaching hospital of Italy. Journal of Chemotherapy Vol. 17 n. 5 (560-562) 2005
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