Catheter ablation of atrial arrhythmias in patients after thoracoscopic ablation of persistent atrial fibrillation

Abstract

Aim. To determine the mechanisms of development and approaches to interventional treatment of postoperative atrial tachycardia in patients after thoracoscopic ablation (TA) of atrial fibrillation (AF). Material and methods . The results of thoracoscopic ablation of AF in 46 patients were analyzed, of which 19,5% (n=9) had atrial tachycardia after the procedure. Radiofrequency ablation (RFA) was conducted in these patients after a 3-month blanking period. Regardless of tachycardia type, the threedimensional reconstruction including high-density right and left atrial (LA) voltage mapping was performed in order to visualize the lesions, pulmonary veins and LA posterior wall isolations. After RFA and sinus rhythm restoration, re-mapping was performed to assess conduction block and absence of electrical activity in the lesion zones. Results. Complete pulmonary vein (PV) isolation was verified in 55,5% of patients (n=5). In 44,4% (n=4), there were residual PV fractionated potentials without conduction with LA. In 22,2% of subjects (n=2), we identified typical atrial flutter (AFL), which was terminated by RFA in cavotricuspid isthmus (CTI). There were 77,7% (n=7) of patients who were diagnosed with atypical LA flutter; 66,6% (n=6) of them had conduction reconnection at the thoracoscopic box-lesion line. Perimitral AFL with slow conduction zone which was located on the anterior wall of LA was verified in 11,1% of patients (n=1). The effective RFA was performed in these areas. Two main factors affecting failed ablation were LA volume and body mass index (BMI). In patients with arrhythmias after TA, LA volume was 180,2±35,6 ml vs 158,34±38,5 ml in patients with sinus rhythm. BMI was 30,8±3,1 kg/m2 and 28,9±3,9 kg/m2, respectively. The mean follow-up was 9,8±2,7 months. All patients after catheter ablation maintained a stable sinus rhythm. Conclusion. Atrial tachycardia after TA is caused by the gaps in box-lesion lines. The main predictors of gaps are high values of LA volume and BMI. The high-density mapping increases the effectiveness of RFA. Combination of epicardial and endocardial accesses is the most effective approach to treatment of patients with persistent AF.