Abstract
SummaryThe twenty‐four hour urinary excretions of the catecholamines were measured in 39 psoriatic patients and compared with the results obtained for 97 healthy volunteers from a previously published study using a similar technique. The psoriatic patients showed significantly lower adrenalin levels (p<0.001) and significantly higher noradrenalin (0.001<p<0.01) and dopamine levels (p<0.001). A significant positive correlation (p<0.05) was found between adrenalin excretion and % skin involvement. These preliminary findings lend further support to the theory of cyclic nucleotide axis involvement in the aetiology of psoriasis.
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