Abstract
An efficient catalytic asymmetric oxidation reaction of N-benzoyl-1,5-benzothiazepines using a chiral titanium complex formed in situ from Ti(O-iPr)4, (R, R)-diethyl tartrate was developed. This reaction is helpful for the synthesis of the active form of (E, aS, 1S)-sulfoxide of N-benzoyl-1,5-benzothiazepines which should be recognized by vasopressin receptors. Furthermore, a prospective dynamic kinetic resolution utilizing this system was achieved.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
