Abstract

Catalase activity in the erythrocytes of beagle dogs was biochemically assayed and compared with human erythrocytes. The mean value of catalase activity in dog erythrocytes was about one-thirtieth of that of human erythrocytes. Wide variations in catalase values were found in the dog erythrocytes. Among 17 dogs tested, one female dog was found to be acatalasemic and two male and one female dogs hypocatalasemic. These four catalase-deficient animals came from a single brood together with one normal female dog. Although the catalase activity of the acatalasemic dog erythrocytes was difficult to detect, the liver and kidney showed half the catalase activity of normal dogs.

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