Abstract
Castleman’s disease is also known as angiofollicular lymph node or giant lymph node hyperplasia. It occurs most commonly in adults, equally in men and women. There are two clinical presentations as unicentric and multicentric forms. The two main histological types described are the hyaline vascular and the plasma cellular types. In this study, two cases of unicentric, hyaline vascular Castleman’s disease with parotid gland and neck involvement which were surgically excised and histopathologically diagnosed are presented. (Gazi Med J 2012; 23: 69-72)
Highlights
Castleman’s disease (CD), known as angiofollicular lymph node or giant lymph node hyperplasia, is a rare lymphoproliferative disorder that was first described by Benjamin Castleman in 1954 [1]
The two main histological types described for CD are the hyaline vascular type and the plasma cellular type
We present a 36-year-old woman with a solitary mass in the right neck region and a 52-yearold woman with a mass arising from the right parotid gland who were reported as the hyaline vascular type of CD upon histopathological examination
Summary
Castleman’s disease (CD), known as angiofollicular lymph node or giant lymph node hyperplasia, is a rare lymphoproliferative disorder that was first described by Benjamin Castleman in 1954 [1]. It occurs most commonly in adults, in men and women. Multicentric CD, most of which are the plasma cell type, behaves aggressively, presents with multiple lymph nodes, constitutional symptoms. This case was presented as a poster at the 33th Turkish National Congress of Otorhinolaryngology and Head & Neck Surgery, 26-30 October 2011, Antalya
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