Castleman's disease: A rare case report and review of literature

Abstract

Castleman's disease – also known as giant lymph node hyperplasia – is a rare pathology, poorly understood. Described for the first time in 1954, it is considered a lymphoproliferative disorder that manifests without any other obvious symptoms and may be confused with other causes of lymph nodal enlargement. We are reporting in this paper the case of a 30-year-old Maldivian female who presented to our surgical OPD with a right cervical large solitary soft tissue lesion. All the investigations were negative except for a large highly vascularized unicentric soft tissue mass measuring around 4 cm in the anterior triangle of the neck seen by the ultrasound separable from all other surroundings. An excisional biopsy & complete resection was done under general anesthesia in the operation theater of a Maldivian Regional hospital. Unicentric Castleman's disease as a diagnosis was confirmed based on the final histopathological study of the specimen, and the absence of other cervical and extra-cervical lymphadenopathy. The patient doesn't have recurrence or newly developed lymph nodes at the time of reporting this article.