CASPR2 antibody encephalitis presenting as transient epileptic amnesia

Abstract

Transient epileptic amnesia (TEA) is an underrecognized form of late-onset temporal lobe epilepsy, generally occurring between the ages of 50 and 70, and manifesting as ictal episodes of transient amnesia, either retro- and/or anterograde, of variable duration. The episodes are mostly short (≤ 1 h), but can last for hours and thereby mimic benign transient global amnesia (TGA) [1]. In addition to episodic amnesia, the diagnosis of TEA may be suggested by complaints of interictal cognitive problems.