Abstract
IntroductionIrreversible electroporation (IRE) is a promising technique for the focal treatment of soft tissue tumors. Even though the local application of an excessive electric field is a potential cause of cardiac arrhythmias, initial clinical studies have shown that IRE is generally safe when cardiac gating is employed.Case descriptionIn this case report, we observed an episode of ventricular extrasystoles without hemodynamic changes during which time the synchronization device failed to operate properly, with pulses delivered not in the absolute refractory period but in the relative refractory period.Discussion and evaluationAt present, persons performing IRE must keep in mind that there is a small but real risk of synchronization failure even when a cardiac synchronization device is used.ConclusionIt is advisable to err on the side of caution when treating lesions near the heart.
Highlights
Irreversible electroporation (IRE) is a promising technique for the focal treatment of soft tissue tumors
We describe the IRE treatment of metastatic liver lesions located in close proximity to the inferior border of the heart
The authors of that study stated that when performing IRE ablation, in order to avoid inducing ventricular arrhythmias, the distance from the heart should be greater than 1.7 cm or IRE should be performed in synchronized mode (Deodhar et al 2011)
Summary
Irreversible electroporation (IRE) is a promising technique for the focal treatment of soft tissue tumors. IRE may offer two major potential advantages over commonly employed radiofrequency (RF) thermal ablation approaches for the treatment of hepatic lesions.
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