Abstract
Soft tissue defects caused by traumas and other diseases are currently treated with autograft, allograft, and commercially available implants. Despite the advancements in the current treatment modalities, researchers still face significant challenges in repairing the soft tissues. Current challenges in the conventional therapeutic approaches have prompted scientists to develop regenerative engineering approaches for soft tissue regeneration. The regenerative engineering techniques offer a novel solution by converging the fields of tissue engineering, advanced material science, stem cell science, physics, developmental biology, and clinical translation for the reconstruction of soft tissue. In this regard, several different studies have been done to explore the use of various biomaterials with different cell sources and growth factors. Here, we discussed the current treatment strategies including the clinical trials and the new developments for soft tissue regeneration.
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