Abstract
This paper describes two cases of oral granular cell tumours with an atypical clinical presentation; both are in females aged between 45 and 63 years of age. Granular cell tumours are unusual soft tissue neoplasm of neural or Schwann cell origin. Oral GCTs usually present clinically as pink or yellow small sessile lesions. GCTs are usually benign in nature; however they can present in a malignant form in fewer than 2% of cases. In benign cases treatment is surgical and usually curative with extremely low recurrence rates.
Highlights
A granular cell tumour (GCT) is an uncommon soft tissue neoplasm, first discovered in 1926 by Abrikossoff who termed it a “Myloblastenmyome” as it was postulated to be of myogenic origin [1]
It is thought to be of neural or Schwann cell origin this is supported by the positive staining of GCTs for S-100 as outside the central nervous system S100 is found only in Schwann cells [2]
The nodular mass is hard in consistency and generally reveals an intact overlying epithelium
Summary
This paper describes two cases of oral granular cell tumours with an atypical clinical presentation; both are in females aged between 45 and 63 years of age. Granular cell tumours are unusual soft tissue neoplasm of neural or Schwann cell origin. Oral GCTs usually present clinically as pink or yellow small sessile lesions. GCTs are usually benign in nature; they can present in a malignant form in fewer than 2% of cases. In benign cases treatment is surgical and usually curative with extremely low recurrence rates
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