CASE SERIES OF HYPOKALEMIC PERIODIC PARALYSIS

Abstract

The Periodic paralysis syndrome are described as channelopathies that manifest as abnormal, often potassiumsensitive,muscle-membrane excitability and lead clinically to episodes of accid weakness or paralysis, sometimes in association with abnormalities of the plasma potassium level. Strength is initially normal between attacks, but progressive myopathic weakness may develop in up to one-third of patients. Hypokalemic periodic paralysis characterized by attacks that tend to occur on awakening,after exercise, or after a heavy meal and may last for several days. Patients should avoid excessive exertion. A low-carbohydrate and low-salt diet may help prevent attacks.An ongoing attack may be aborted by potassium chloride given orally or by intravenous drip, provided the ECG can be monitored and kidney function is satisfactory. We report a case series of 3 gentlemen with sudden onset paralysis of extremities and laboratory evaluation revealed a low potassium level. The patient paralysis resolved upon repletion of his low potassium and was discharged with no neurologic decits.