Abstract
BackgroundAngiomyolipoma (AML) is a common, chronic disease usually localized in kidney and liver organs; but occurring frequently outside the kidney or liver.Case presentationWe describe an unusual case of a 62-year-old female patient with AML in the middle ear. She presented with left earache, tinnitus and hearing loss. Preoperative computed tomography and magnetic resonance imaging seemed to reveal a middle ear cholesteatoma. The patient underwent surgical resection of this lesion, and the AML was finally confirmed by histopathological examination. The patient was discharged on the 8th postoperative day and did not seek further treatment.ConclusionsExtraperitoneal AML is rare and accurately identified by histopathology. The recommended management is surgery for AML in the middle ear.
Highlights
Angiomyolipoma (AML) is a common, chronic disease usually localized in kidney and liver organs; but occurring frequently outside the kidney or liver.Case presentation: We describe an unusual case of a 62-year-old female patient with AML in the middle ear
Angiomyolipoma (AML) is the most common benign tumour of the kidney and is related to the tuberous sclerosis complex, which is composed of vascular endothelial cells, smooth muscle cells and fat cells [1,2,3]
AML is frequently found among women with lymphangioleiomyomatosis [5]
Summary
Case presentation: We describe an unusual case of a 62-year-old female patient with AML in the middle ear. She presented with left earache, tinnitus and hearing loss. AML is frequently found among women with lymphangioleiomyomatosis [5] Both incidental and disease-related AML are caused by mutations in the TSC1 or TSC2 genes that control cell growth and proliferation [6]. This tumour outside the kidney is extremely rare. Given the paucity of information about this tumour, the aim of this study was to present a case, the first AML reported in the middle ear, to describe the clinical features and a treatment protocol
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