Abstract
Primary thyroid lymphoma is a rarely encountered clinical entity that occurs mainly in elderly females. We present a case of B-cell origin thyroid lymphoma. The diagnosis was made by combined histology and immunochemistry. A 79-year-old woman presented with an enlarging neck mass with compression signs, dysphagia and pressure sensation around the neck. On admission, the sonogram of the thyroid gland showed an enlarged mass and CT scan demonstrated diffuse enlargement of the thyroid extending on the anterior chest wall. After total thyroidectomy, the histological investigation revealed the presence of a diffuse large B-cell non-Hodgkin’s lymphoma without other loci from the systemic staging. The patient underwent chemotherapy and radiation therapy. Clinicians should include primary thyroid lymphoma in the differential diagnosis of a rapidly enlarging thyroid mass.
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