Abstract

Primary dural lymphoma is a subentity of primary leptomeningeal lymphoma which represents 0.1% of all non-Hodgkin's lymphomas. Only five cases have been reported so far. We report a very rare case of primary dural-based lymphoma in a 14 year-old boy presenting with mass effect. The patient was managed with excision of the lesion and removal of the involved bone. Post-operatively, the patient showed good recovery. He was then referred to the oncology unit for further chemo- and radiation therapy. A high index of suspicion should therefore be kept in order to diagnose the condition in a timely fashion and then plan for appropriate management since diffuse large cell lymphoma has a relatively benign clinical prognosis.

Highlights

  • Primary dural diffuse large B-cell lymphoma (DLBCL) is an extremely rare entity with only five cases reported so far[1]

  • A high index of suspicion should be kept in order to diagnose the condition in a timely fashion and plan for appropriate management since diffuse large cell lymphoma has a relatively benign clinical prognosis[4]

  • We report a case of a primary dural based DLBCL in a 14 year-old boy presenting with herniation syndrome, who improved after surgical excision and is currently on chemotherapy

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Summary

Introduction

Primary dural diffuse large B-cell lymphoma (DLBCL) is an extremely rare entity with only five cases reported so far[1]. We report a case of a primary dural based DLBCL in a 14 year-old boy presenting with herniation syndrome, who improved after surgical excision and is currently on chemotherapy. Previous treatment history revealed that the patient had been taken to India 1 month back, where fine needle aspiration cytology (FNAC) of the scalp lesion in the parietal region had revealed Non-Hodgkin’s lymphoma. Surgery revealed a duralbased lesion (Figure 5) that was moderately vascular, soft and friable in consistency with involved bone showing a moth-eaten appearance (Figure 6). Both extra- and intra-dural extension (Figure 7 and Figure 8) of the lesion was seen. Patient has been started on chemotherapy and is advised for regular follow-ups

Discussion
Findings
Oberling C

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