Case Report: Peripartum periventricular leukomalacia resulting in cerebral palsy associated with placenta previa in Japan

Shunji Suzuki

doi:10.12688/f1000research.22878.3

Abstract

Intrapartum fetal heart rate monitoring abnormalities had been reported to correlate with decreased umbilical artery base excess associated with neonatal seizures. However, we present an infant born at 35 weeks of gestation diagnosed with cerebral palsy associated with periventricular leukomalacia (PVL) without fetal heart rate (FHR) monitoring abnormalities, According to the summary reports of PVL cases published on the home page of the Japan Obstetric Compensation System for Cerebral Palsy (JOCSC)), the percentage of placenta previa without FHR monitoring abnormalities in the cases of PVL was 5.7% (12/209), which seemed to be higher than the total percentage of placenta previa reported in Japan (0.3-0.5%).

Highlights

University of Ulsan, Seoul, Any reports and responses or comments on the article can be found at the end of the article
A review and analysis of the summary reports of periventricular leukomalacia (PVL) cases published on the home page (HP) of the Japan Obstetric Compensation System for Cerebral Palsy (JOCSC) was conducted
We conclude that placenta previa may be a risk factor for antenatal- and peripartum PVL resulting in cerebral palsy (CP) in Japan

Summary

Euiseok Jung South Korea

University of Ulsan, Seoul, Any reports and responses or comments on the article can be found at the end of the article. In an earlier study in Japan, frequent moderate variable deceleration on fetal cardiotocogram (CTG) was observed to be a cause of antenatal PVL in premature infants[1]. Review and analysis of PVL cases on JOCSC To re-examine the previous findings in Japan regarding PVL cases[1,2], we reviewed the summary reports of antenatal- and peripartum PVL cases published on the HP of the JOCSC launched in 20095. This is a free to access resource, and the cause analysis reports (summary reports) of the patients can be accessed here: http://www.sanka-hp.jcqhc.or.jp/documents/ analysis/index.html. The following variables were extracted from the reports:fetal heart rate decelerations, intrauterine infection, placental abruption and placenta previa. The percentage of placenta previa in the cases of PVL was 5.7% (12/209), which seemed to be higher than the total percentage of placenta previa reported in Japan (0.3-0.5%)[6]

Discussion

Japan Society for Obstetrics and Gynecology

11. Suzuki S