Abstract
Introduction: Subacute sclerosing panencephalitis (SSPE), frequently referred as Dawson disease, is a kind of sclerosing panencephalitis, and is an uncommon long-term, continuous cerebral inflammatory condition triggered by a gradual infection with particular faulty types of hyper mutated measles virus.
 Main Symptoms and/or Important Clinical Findings: Patient came with the complaint of gait abnormalities, sudden fall while walking, loss of speech, staring look, abnormal smile and loss of bladder control, hemiplegia and contracture of all four limbs, seizures, Grade III Malnutrition.
 The Main Diagnoses, Therapeutic Interventions, and Outcomes: Patient undergone investigation i.e. Blood Test: Hb- 9.8 gm%, TLC- 14,700/mm, Platelet- 2.24 lacs /cu.mm, Total Protein- 8.4 g/dl, HCT- 29.8, Serum Bilirubin- 1.0mg/dl, ALP- 99IU/L, Serum Urea-32mg/dl,SerumCreatinine-0.5mg/dl,SerumSodium-153meq/L,SerumPotassium-.2mmol/L. .CSF igg Measles test was done EEG which revealed burst of periodic complexes with well-preserved back ground activity. Doctor manages with Tab. Valparin 200mg BD, Tab. Frisium 5mg BD, Tab. Baclofen10mgBD,Tab. Samion D3 OD, Syp Q-Carni 5ml BD, Tab. Augment375mg BD.
 Outcome: After treatment, the child showed some improvement. The patient was admitted to Pediatric Ward No- 22, AVBRH with known case of Subacute sclerosing panencephalitis (SSPE) and he had complaint of swelling over right jaw with caries tooth since4month.
Highlights
Subacute sclerosing panencephalitis (SSPE), frequently referred as Dawson disease, is a kind of sclerosing panencephalitis, and is an uncommon long-term, continuous cerebral inflammatory condition triggered by a gradual infection with particular faulty types of hyper mutated measles virus
Patient was diagnosed with Subacute Sclerosing of Panencephalitis (SSPE) since 7 year of age
Face was oval in shape, black in color, A male child of 12 years was brought to AVBRH on 25th June 2021 by her parents with the complaint of swelling over the right jaw with carries tooth since 4 month with a known case of Subacute sclerosing panencephalitis (SSPE) associated with Gait abnormalities, sudden fall while walking, loss of speech, staring look, abnormal smile, and loss of bladder control, hemiplegia and contracture of all four limbs, seizures
Summary
Subacute sclerosing panencephalitis (SSPE) is neurodegenerative entropy that affects youngster and adolescent central nervous systems. It’s a gradual and sustained infectious illness produced by a faulty measles virus [1]. Dawson described for the first in stancein1933 kid having gradual mental decline with spontaneous motions whom, atnecropsy, was discovered to have a prominent engagement of grey matter with numerous neuronal inclusion bodies [2] In emerging nations such as India and Eastern Europe, the prevalence of SSPE tends to be high. Dyken criteria were first designed to aid in the diagnosis of SSPE. Two main and one minor criterion are required for diagnosis when using this new recommended diagnostic criteria, which is part of the SSPE. The most prevalent symptoms include myoclonus, cognitive deterioration, poor academic performance, and behavioral problems. In the therapy of SSPE, antiviral medicines and immunosuppressive agents are employed [7]
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