Case Report on Primary Infertility with Hypothyroidism and Diabetes Mellitus

Abstract

Introduction: Infertility is the inability, by natural means, of an animal to reproduce. Typically, adult species are not in their normal state of health. A woman who is unable to conceive well will define infertility as unable to bear a full-term pregnancy. Because of any ejaculating disease, and any declining sperm count, men are directly liable for 30-40% infertility. The WHO estimates the overall prevalence of primary infertility in India at 3.9% and 16.8%. Fertility estimates differ widely between India and 3.7% in Utter Pradesh and Maharashtra.
 Case Presentation: On 9/12/2020, a 38-year-old female came for In Vitro Fertilization with a known case of primary infertility in AVBR Hospital, Wardha. Her complaint was inability to conceive for 4 years, irregular menses, headache, sleep disturbance, loss of appetite. She was admitted for in-vitro fertilization therapy for the 2nd cycle. She had a history of hypothyroidism for 8 years for which she has been taking Thyrox 50mg OD tablet and has Diabetes Mellitus for one year since she is taking Metformin 500mg BD tablet. Instead, she has no concerns about asthma, tuberculosis, epilepsy, etc. On 9/12/2020, she underwent an embryo transfer.
 Diagnostic Evaluation: The diagnostic hysteroscopy was conducted at the private hospital in Amravati 2 years ago. She has been diagnosed with nullipara for 4 years as a primary infertility. She has already undergone 2 cycles of Intra Uterine Insemination (IUI) and 1 cycle of in vitro fertilization.
 Hysterosalpingography: Both fallopian tubes are normal & patent uterus is normal.
 Conclusion: There is multifactorial infertility. In both men and women, anatomy, physiology, the environment, hormones and genetics all play a role in causing infertility. Therefore, in the coming years, it is a very important problem and research in this zone is very essential.