Case Report of Treatment Resistant Pyoderma Gangrenosum

Abstract

This is a case of a 38-year-old married female diagnosed with Pyoderma Gangrenosum (PG) for 4 years. This patient was very anxious and frustrated. The patient was using all the standard treatments for PG, oral steroids 40mg/day, colchicine 2mg/day, topically tacrolimus 0.1%, topically metronidazole, oral 3rd generation of cephalosporin antibiotics 1gm/day, and oral dapsone 100mg/day but lesion was getting worse. The patient family and her husband were very supportive and all the negative options of physical and mental abuse, and not taking proper medicine have been completely ruled out by taking a detailed history from the patient alone. The patient is willing to get the cure and take and apply for all the medicines properly. All the other diseases have been ruled out that can be associated with PG such as inflammatory bowel diseases, trauma, vasculitis, arthritis, etc. The patient has been to many physicians but has not been able to get better and the lesion is getting worse day by day and because of this patient started the symptoms of depression and start losing weight. PG is a very worrisome disease and usually, PG cure rate is unpredictable. Patients having PG have emotional problems too because of lesions. The patient usually isolates herself from society and lost all her confidence.