Case Report of Arm Kimura Disease with Atypical MR Finding

Abstract

Kimura disease is a rare chronic inflammatory condition of unknown origin that occurs mainly in young Asian male patients. Kimura disease is characterized by painless subcutaneous swelling and lymphadenopathy of the head and neck, associated with peripheral blood eosinophilia and increased serum IgE. According to some previous reports about a rare form of Kimura disease of the upper arm, soft tissue masses of the subcutaneous fat layer were demonstrated in the medial trochlear area, which showed strong and homogenous enhancement with marked perilesional edema and fat infiltrations on enhanced magnetic resonance imaging (MRI). In this case report, we introduce a case of Kimura disease of the upper arm in a 13-year male patient, which was seen as a well-marginated soft tissue mass without perilesional edema or fatty infiltrations on MRI. In this case study, we discuss the characteristics of the clinical and pathologic findings associated with unusual MRI findings, and report the Kimura disease with a different pathophysiology by anti-inflammatory drugs.