Case Report of a Rare Intracranial Tumour

Abstract

A meningeal Solitary Fibrous Tumour (SFT), also called hemangiopericytoma is a fibroblastic type of mesenchymal tumour. These tumours often show a rich, well-branched vascular pattern that encompasses a histological spectrum of tumours which was previously classified separately as meningeal SFT and haemangiopericytoma. Discovery of NAB2-STAT6 fusion in a vast majority of haemangiopericytomas and solitary fibrous tumours indicates a possibility of morphological continuum. Herein, authors report a case 65-year-old female known case of hypertension and type II diabetes mellitus, presented with complaint of headache since 2 months and left side weakness since 3 weeks. On clinical examination, she was found to have motor weakness of left upper limb and lower limb with no sensory deficit. Magnetic resonance imaging showed an extra axial, right frontoparietal convexity, solidly enhancing tumour with transosseous invasion and the imaging features were suggestive of atypical meningioma. After craniotomy, immunohistochemical evaluation showed tumour cells were strongly positive for CD34 and STAT-6 exhibited the characteristic nuclear localization.The case was reported as Solitary fibrous tumour/Haemangiopericytoma-Grade II. The patient was advised adjuvant radiotherapy but deferred treatment. Regular follow-up after 2 years post surgery has shown that the patient is disease free.