Case report of a combined albendazole and praziquantel therapy in an adult female with neurocysticercosis and generalized tonic-clonic seizures

Abstract

The use of albendazole monotherapy has been favored as the treatment option for neurocysticercosis. This case reports an incidence of neurocysticercosis in a 32-year-old woman who presented to the emergency department with a generalized tonic-clonic seizure. Neurocysticercosis was confirmed by MRI of the brain and positive Taenia solium serologic test. The patient was treated with combined dual therapy of albendazole and praziquantel at standard doses for a minimum effective duration of 14 days in the setting of scarce patient resources. She tolerated therapy without any adverse reactions and remained seizure free. Repeat MRI scan post-treatment revealed the complete eradication of cysticerci. Clinicians should be aware of and consider the efficacy and safety of combined albendazole and praziquantel therapy for the treatment of neurocysticercosis.