CASE REPORT: MIXED CONNECTIVE TISSUE DISEASE (MCTD)

Abstract

Background: The term mixed connective tissue disease (MCTD) was coined by Sharp and colleagues in 1972 proving to that mixed connective tissue disease a systemic autoimmune disease which involves antibodies like anti-sm, Ro-52 recombinant, nucleosome,anti-Jo-1,anti ds-DNA,etc. Case presentation: A 28-year-old lady presented with complaints of multiple joint pain since 3 days along with weakness. She also complained about low grade fever associated with chills and rigor, vomiting, headache and body ache. There was involvement of morning stiffness in small joints of fingers and toes. Reports were done and she was eventually treated according to it. Conclusion: The work has reported a rare case of an adult patient with MCTD characterized by a severe multiple joint pain along with severe weakness and positive AntiU1-RNP levels and was treated with corticosteroid (Prednisolone), Methotrexate and analagesic (Tramadol and Paracetamol).