Abstract
Case report: High-volumetric atypical hemihepatectomy in patient with colorectal cancer with extensive metastatic disease
Highlights
Colorectal cancer is the third most common cancer in men and the second in women worldwide with the highest estimated mortality rates in both sexes in Central and Eastern Europe - 20.3 per 100,000 for men, 11.7 per 100,000 for women
Metastases of colorectal cancer are primarily found in liver due to drainage through the portal system
Life expectancy might be prolonged by the hepatic resection, which is thought to be the most effective method of therapy, as it is possible to remove up to 80% of hepatic parenchymatous tissue
Summary
Colorectal cancer is the third most common cancer in men and the second in women worldwide with the highest estimated mortality rates in both sexes in Central and Eastern Europe - 20.3 per 100,000 for men, 11.7 per 100,000 for women. Two months after neoadjuvant chemotherapy was finished, patient received anterior resection of rectum and transmesorectal excision with preventive iliostoma. Two months after MRI examination first stage of surgical management of liver metastases was done-atypical resection of Sg 2, Sg 3, Sg 4a and Sg 4b with following right portal vein branch ligation and hepatoduodenal region lymphadenectomy (Figure 5). After first stage of operation patient received seven FOLFIRI and five bevacizumab courses due to allergic reaction for FOLFOX regimen. Two years after diagnosis of rectal malignancy, received neoadjuvant and adjuvant chemotherapy and surgical intervention, patient was considered disease-free with no tumour focuses found in CT and MRI examinations (Figure 8). No data about progression of oncologic process are found at the moment
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