Case report: Giant congenital pulmonary airway malformation initially managed and resected on ECMO

Abstract

Abstract Congenital pulmonary airway malformations (CPAM) are a common congenital anomaly, occurring as a result of aberrant formation of pulmonary lobes or segments. Many patients with CPAM are treated with postnatal surgical excision within 1-year of age. CPAM that are enlarged to the point of causing an intrathoracic mass effect may cause hydrops fetalis. Fetuses affected in this way may require prenatal intervention and immediate postnatal intervention. We herein report a case of a large CPAM causing hydrops fetalis and postnatal respiratory failure, treated by an aggressive prenatal and postnatal multidisciplinary approach, culminating in resection of the lesion while on extracorporeal membrane oxygenation (ECMO) support.