Case Report: Conjunctival Intraepithelial Neoplasia

Abstract

Conjunctival intraepithelial neoplasia (CIN) is a dysplastic lesion of the conjunctiva and is the most common tumor of the ocular surface. CIN typically presents as a fleshy, gelatinous lesion that is typically located at the limbus. Risk factors include ultraviolet light exposure, immunocompromised state, history of smoking and human papilloma virus (HPV). Case Report: We present a case of CIN in a 76 year-old African American patient whose only complaint was of dry eye symptoms. Anterior segment examination revealed a gelatinous, vascularized lesion on the bulbar conjunctiva of the right eye. Excisional biopsy revealed a diagnosis of CIN with positive margins. The patient was treated with topical interferon alpha 2b drops. Conclusion: CIN is a neoplastic disorder that has a relatively favorable prognosis with treatment which includes both topical and surgical management. Careful anterior segment examination is crucial in detecting these lesions with prompt referral for treatment. CE Notification: This article is available as a COPE accredited CE course. You may take this course for 1-hour credit. Read the article and take the qualifying test to earn your credit. Click here to Enroll (https://www.crojournal.com/conjunctival-intraepithelial-neoplasia)