Case Report] Clear Cell Carcinoma of the Ovary with Disseminated Intravascular Coagulation and Haemoperitoneum with Tumour Rupture

Abstract

We report a 34-year-old woman with haemoperitoneum and acute disseminated intravascular coagulation (DIC) following rupture of ovarian clear cell carcinoma (OCCC), the first documented case. Although DIC is known to be associated with ovarian cancer, acute DIC with bleeding in clear cell variants is not reported. A patient with a right adnexal lesion was found to have anaemia with thrombocytopenia. Intra-abdominal bleeding with the rupture of a malignant ovarian cyst associated with DIC was found to be the cause. After surgery, DIC resolved, indicating OCCC can be the aetiology for acute DIC and bleeding. Practitioners must know this rare but potentially fatal association between OCCC and acute DIC.