Abstract

This is a patient with post-partum hemorrhage (PPH), secondary to uterine atony managed with sub-lingual misoprostol 1000μg. Hyperpyrexia resulting from the route of administration of the drug and the clinical presentation of the condition, give rise to diagnostic difficulties and special interventions during the management process. A literature review on misoprostol, its pharmacological profile and side effects concluded that sub-lingual misoprostol results in a maximum concentration and is associated with the highest incidence of side effects as compared to other routes of administration.

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