Abstract
Case Profiles of Noninvasive Functional Brain Imaging as an Alternative to Cortical Stimulation Mapping
Highlights
Presurgical localization of eloquent cortex in epilepsy and brain tumor patients has traditionally been performed using cortical stimulation mapping (CSM), either intra- or extraoperatively, using subdural electrodes
While CSM is considered the “gold standard” in presurgical functional mapping, recent literature has highlighted the merits of non-invasive brain mapping techniques as possible alternatives to CSM, for outlining the cortical mapping of the cortical regions underlying motor, somatosensory and language functions [1]
We highlight the utility of non-invasive brain mapping methods, in two presurgical cases, where clinical recommendations to pursue alternative treatments to surgical intervention were facilitated by combined concordance of magneto encephalography (MEG) and transcranial magnetic stimulation (TMS) information
Summary
Roozbeh Rezaie, James W Wheless, Frederick A Boop2,4* and Shalini Narayana. We first report an instance of preserved sensorimotor function within an area of frontal polymicrogyria coincident with the ictal onset zone in a female with intractable symptomatic partial epilepsy; second, we present findings from a female patient where language localized to the boundary of a left temporal lobe ganglioglioma. In both cases, the outcome of the non-invasive techniques was deemed to be of sufficient utility to defer surgery and seek alternative treatment measures, in order to preserve function and reduce morbidity.
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