Abstract

The presented article features the management of a high-risk patient with polymorbid pathology: cancer, stroke and venous thromboembolism. In spite of anticoagulant therapy with heparin, unilateral deep vein thrombosis of the lower leg was complicated by a primary episode of verified acute bilateral pulmonary artery thromboembolism of high-risk with hypotension and bilateral infarct-pneumonia. After urgent diagnosis of PE had been made, the following management of the patient in the acute phase was suggested: timely modern replacement artificial ventilation of the lungs for eight days, vasopressor support for six days, anticoagulant therapy, fluid replenishment and effective in its results, enteral nutrition. The pattern of evolving pulmonary hypertension and acute right ventricular dysfunction, coagulation disorders was tracked down. Residual thrombosis proved to linger by detection of steep D-dimer rise on the ninth day of the acute period. The signs of thrombosis persisted despite anticoagulant therapy, with the simultaneous complete disappearance of blood clots according to computed tomography. That was accompanied by severe disorders of the heart rhythm recalcitrant to antiarrhythmic and electropulse therapy. Further treatment in the settings of a specialized center revealed occult extra routes of impulse conducting that justified necessity of catheter ablation. On the ninetieth day the patient was alive and stable. Presented approach of diagnostic and therapeutic steps proved to be effective.

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