Abstract
A 45-year-old woman complained of a painless breast mass, sized 2.5cm in diameter. It was diagnosed as fibroadenoma of intracanalicular type or benign phyllodes tumor. About one month later, breast mass appeared again, which could not be disappeared by aspiration, and was diagnosed as late onset hematoma. Its wall was coagulated under general anesthesia. Microscopic findings of the hematoma wall showed fibrosarcoma partially including the proliferation of cartilage, and it was proved that the hematoma was malignant phyllodes tumor. She died elevent months later after mastectomy. Inappropriate high levels of serum ALP and RI accumulation (99mTcMDP) in the breast mass were present. This case suggests that ALP (isozyme 3) may be an useful marker of malignant phyllodes tumor with proliferation of cartilage.
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