Abstract

There was a constant searing pain in the right side of the head and a face that was not buying analgesics in a 61-year-old woman, after surgery in 2018 to remove a meningioma in the right frontal lobe followed by a cranioplasty titanium implant. Evaluation of immune status revealed that the allergological test for titanium was positive. According to the results of the MR-study of data for continued growth of the tumor, as well as signs of vasonary conflict of the trigeminal nerve.The possible development of the galvanic syndrome in patient has been suggested. Thus, the decision to remove the titanium implant has been made. During the operation, the presence of galvanic current (from 3–46 μA) on the titanium plate surface was documented and instrumentally confirmed.Under the titanium implant during the operation, ectopic foci of neoosteogenesis were visualized. The condition improved in the form of a complete regression of pain syndrome after removing the titanium implant.The present clinical case is the world’s first description of the development of galvanic syndrome on the surface of titanium cranioplastic mesh. The presence of electroplating repair of bone tissue can be a new step in solving the problem of closing skull defects in neurosurgical patients.

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