Case of Angiolymphoid Hyperplasia with Eosinophilia Associated with Anti-TNF Inhibitor

Singh Neeraj,Sundquist Britta,Kaushik Prashant

doi:10.23937/2469-5750/1510040

Abstract

Case of Angiolymphoid Hyperplasia with Eosinophilia Associated with Anti-TNF Inhibitor

Highlights

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign, and insidious condition that presents as nodules, papules, and plaques that involve the dermis, subcutaneous tissue, and adjacent lymph nodes [1]
When he was diagnosed with rheumatoid arthritis, the salsalate was replaced with prednisone 60 mg by mouth once daily and methotrexate 12.5 mg by mouth once weekly
Palmoplantar pustular psoriasis has been associated with etanercept use, while leukocytoclastic vasculitis, pustular folliculitis, and psoriasiform dermatitis have been associated with infliximab use [3]

Summary

Introduction

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign, and insidious condition that presents as nodules, papules, and plaques that involve the dermis, subcutaneous tissue, and adjacent lymph nodes [1]. It is typically seen in adults, and its etiology is unknown [1]. It is most often located at the head or neck, rare cases have involved the torso and genitals [1] Histological studies of this condition reveal proliferation of small to mediumsized blood vessels, often forming a lobular architecture [1]. They are lined by enlarged endothelial cells, which can occlude arteries and create a cobblestone appearance under microscopic examination [1]

Results

Discussion

Conclusion