Abstract

Myeloproliferative disorders (MPDs) are defined as clonal stem cell diseases. the cardiovascular system is involved in 4 to 21% of MPD cases, presenting as acute ischemic coronary artery disease, valvular heart involvement, pericardial involvement, aortitis, thrombosis of major vessels, pulmonary embolism, systemic and pulmonary hypertension. Acute coronary syndrome may be the first manifestation of myeloproliferation.

Highlights

  • Myeloproliferative disorders (MPDs) are defined as clonal stem cell diseases

  • Acute coronary syndrome may be the first manifestation of myeloproliferation

  • MPDs are neoplastic disorders characterized by proliferation of the myeloid stem cell

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Summary

Introduction

Myeloproliferative disorders (MPDs) are defined as clonal stem cell diseases. The cardiovascular system is involved in 4 to 21% of MPD cases, presenting as acute ischemic coronary artery disease, valvular heart involvement, pericardial involvement, aortitis, thrombosis of major vessels, pulmonary embolism, systemic and pulmonary hypertension. Acute coronary syndrome may be the first manifestation of myeloproliferation

Clinical data
Pathological findings
Discussion
Findings
Personal history of thrombosis Positive Negative Negative
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