Abstract
The general function of the actin cytoskeleton is to shape, support, and move membranes. Actin regulatory proteins guide the self-organization of actin into functional structures like stereocilia, lamellipodia, filopodia, and ultimately cell motility. Among these regulatory proteins is Capping Protein. Capping Protein is a heterodimer that terminates individual actin filament elongation; yet it promotes branched network assembly via Arp2/3, competes with Nucleation Promoting Factors (NPF) to nucleate barbed ends, and is essential for the growth of polarized, force-generating actin networks.
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