Carl W. Gottschalk Distinguished Lecture of the American Physiological Society Renal Section

Abstract

AnnouncementsCarl W. Gottschalk Distinguished Lecture of the American Physiological Society Renal SectionPublished Online:01 Apr 2011https://doi.org/10.1152/ajprenal.00098.2011This is the final version - click for previous versionMoreSectionsPDF (140 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmail Jeff Garvin, PhD, will present the Carl W. Gottschalk Lectureship at the annual Experimental Biology meeting on April 11, 2011, in Washington, DC. Dr. Garvin is a well-respected leader in renal physiology and hypertension, whose work has gained recognition over his career.Dr. Jeff. GarvinDownload figureDownload PowerPointDr. Garvin earned his PhD at Duke University under the mentorship of Dr. Lazlo Mandel. There he began his interest in ion transport, identifying sodium channels in the toad bladder and tongue. He then joined the lab of Mark Knepper, PhD at the National Institutes of Health (NIH) as a postdoctoral fellow. During this period, he carried out a series of very influential studies on ammonium transport in proximal tubules and thick ascending limbs. These studies established beyond any doubt that both renal tubule segments are capable of significant transport of ammonium ions. This was an extremely important set of observations, which added substantially to our understanding of renal acid base transport in the mammalian kidney.At NIH, he developed a myriad of technical skills, which provided a solid basis for his research career. However, his work generated from the perfusion of isolated rat proximal tubules in vitro has led to his most novel findings. In his first faculty position at Henry Ford Hospital in Detroit, Michigan, he focused on the regulation of solute and fluid transport in proximal tubule, thick ascending limb and collecting duct using the isolated, perfused tubule technique and cultured cell techniques. He has shown convincingly that angiotensin II stimulates salt and fluid absorption from the rat proximal tubule and that atrial natriuretic factor inhibits angiotensin II stimulated fluid absorption. Later, he focused on the roles of nitric oxide and superoxide in regulation of solute transport in the thick ascending limb (TAL). One of his most important discoveries was the novel observation that superoxide stimulates salt transport in the TAL. Subsequent studies have tested function in other nephron segments and have explored the regulation of tubuloglomerular feedback. All of these studies have derived from unique applications of difficult techniques to further understanding of salt and water handling by the nephron and how it affects systemic blood pressure.Dr. Garvin has published more than 110 studies and his work has been supported by numerous NIH grants. He presented the Dahl Lecture at the Council for High Blood Pressure Research meeting in 2005. He is currently an Associate Editor of the American Journal of Physiology-Renal Physiology and was Chair of the FASEB Summer Research Conference on Renal Hemodynamics in 2010. In addition, Dr. Garvin has mentored a productive group of trainees now working as independent scientists.Dr. Garvin is an outstanding scientist who continues to make important and novel discoveries in how the kidney regulates salt and water balance. The Renal Section is honored to have Dr. Garvin present the Gottschalk Distinguished Lecture for 2011.The Carl W. Gottschalk Lecture selection committee was composed of Bill Welch (Chair), Tom Kleyman, and David Pollock.This article has no references to display. Previous Back to Top Next FiguresReferencesRelatedInformation More from this issue > Volume 300Issue 4April 2011Pages F1044-F1044 Copyright & PermissionsCopyright © 2011 the American Physiological Societyhttps://doi.org/10.1152/ajprenal.00098.2011History Published online 1 April 2011 Published in print 1 April 2011 PDF download Metrics Downloaded 76 times