Abstract
Currently, we synthesized silver nanoparticles (AgNPs) from the aqueous fruit extract of Carissa carandas L. and evaluated their antioxidant and antibacterial properties. The UV-visible spectra showed a characteristic absorption peak at 412 nm. The Fourier transform infrared (FTIR) spectroscopy exhibits intense peaks at 3430.23cm-1 and 1625.67cm-1 which indicates the involvement of flavonoids and other functional groups in the biosynthesis, capping, and stabilization of AgNPs. From XRD analysis, the average size of AgNPs was estimated to be 45nm. The biogenic AgNPs were spherical in shape and average size range between 10 to 95nm confirmed by HR-TEM analysis. The fabricated AgNPs by fruit extract were monitored for antioxidant activity using DPPH method. The fruit extract of AgNPs (IC50= 946.22μg/ml) had the highest antioxidant activity against standard ascorbic acid. The antibacterial activity was done using Staphylococcus aureus and Escherichia coli bacterial strains. It was found from the results that the bacterial strain S. aureus had the highest antibacterial activity when compared to E. coli and aqueous fruit extract. Thus, the present study exhibits synergistic antioxidant and antibacterial activity which may explore in future clinical treatment.
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