Abstract

Although limited publications address clinical management of symptomatic patients with rabies in intensive care units, the overwhelming majority of human rabies cases occur in the rural setting of developing countries where healthcare workers are few, lack training and drugs. Based on our experience, we suggest how clinicians in resource-limited settings can make best use of essential drugs to provide assistance to patients with rabies and their families, at no risk to themselves. Comprehensive and compassionate patient management of furious rabies should aim to alleviate thirst, anxiety and epileptic fits using infusions, diazepam or midazolam and antipyretic drugs via intravenous or intrarectal routes. Although the patient is dying, respiratory failure must be avoided especially if the family, after being informed, wish to take the patient home alive for funereal rites to be observed. Healthcare staff should be trained and clinical guidelines should be updated to include palliative care for rabies in endemic countries.

Highlights

  • Health care workers (HCW) in developing countries confronted with human cases of suspected or confirmed rabies are not entirely helpless and their role remains essential

  • Management of furious cases with hydrophobia and several days of fever, will require prompt and determined intervention, which must first and foremost alleviate the sensation of thirst, which in our experience can be of mythical proportions.[20]

  • Following a bolus, midazolam can be administered at a dose of 1 mg every 10 minutes by the intravenous route, taking care to reduce doses in dehydrated/hypovolemic patients.[26,29,30]

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Summary

Introduction

Health care workers (HCW) in developing countries confronted with human cases of suspected or confirmed rabies are not entirely helpless and their role remains essential. We wish to remind readers of the specificities of managing rabies cases in the developing setting.

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Conclusion
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