Abstract

The alarmingly high mortality rate and increasing global prevalence of cardiovascular diseases signify the crucial need for early detection schemes. Phonocardiogram (PCG) signals have been historically applied in this domain owing to its simplicity and cost-effectiveness. In this paper, we propose CardioXNet, a novel lightweight end-to-end CRNN architecture for automatic detection of five classes of cardiac auscultation namely normal, aortic stenosis, mitral stenosis, mitral regurgitation and mitral valve prolapse using raw PCG signal. The process has been automated by the involvement of two learning phases. Three parallel CNN pathways have been implemented in the representation learning phase to learn the coarse and fine-grained features from the PCG and to explore the salient features from variable receptive fields involving 2D-CNN based squeeze-expansion. Thus, in the representation learning phase, the network extracts efficient time-invariant features and converges with great rapidity. In the sequential residual learning phase, with the bidirectional-LSTMs and the skip connection, the network can proficiently extract temporal features without performing any feature extraction on the signal. The obtained results demonstrate that the proposed end-to-end architecture yields outstanding performance in all the evaluation metrics compared to the previous state-of-the-art methods with up to 99.60% accuracy, 99.56% precision, 99.52% recall and 99.68% F1- score on an average while being computationally comparable. This model outperforms the previous works using the same dataset by a considerable margin. The high accuracy metrics on both primary and secondary dataset combined with a significantly low number of parameters and end-to-end prediction approach makes the proposed network suitable for point of care CVD screening in low resource setups using memory constraint mobile devices.

Highlights

  • C ARDIOVASCULAR diseases (CVDs), taking away millions of human lives every year, are inciting major concerns in the global healthcare landscape

  • Multiple other cardiac signals involving a wide range of advanced methods such as, electrocardiogram (ECG), angiography, echocardiography, myocardial perfusion imaging (MPI), cardiac computed tomography (CCT), cardiovascular magnetic resonance (CMR), carotid pulse graph, apex cardiogram etc. are being utilized as modern diagnostic tools for effective screening of CVDs as they vividly reflect the overall transthoracic physiological conditions of the cardiovascular system [6], [7]

  • Another work [22] involving in-house dataset, has classified normal, pulmonary and mitral stenosis heart valve diseases utilized discrete fourier transform (DFT) and Burg autoregressive (AR) spectrum analysis for feature extraction

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Summary

INTRODUCTION

C ARDIOVASCULAR diseases (CVDs), taking away millions of human lives every year, are inciting major concerns in the global healthcare landscape. The major contribution of this work is the automatic end to end classification of valvular heart disease from PCG signals using a lightweight CRNN network with no manual feature extraction or preprocessing steps like segmentation, augmentation or replication.The ca-. Pability of the proposed deep lightweight CRNN network to extract salient features directly from PCG signals with minimal training parameters and memory is the main feature of this work. Another highlight is the high performance shown in all matrices.

BACKGROUND
PHYSIOLOGICAL ORIGIN OF CARDIAC AUSCULTATION
NETWORK ARCHITECTURE
SEQUENCE RESIDUAL LEARNING
EXPERIMENTAL SETUP
COMPUTATIONAL EFFICIENCY OF THE PROPOSED MODEL
LIMITATIONS AND SCOPES
Findings
VIII. CONCLUSION
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