Abstract
Introduction. Many cardiovascular risk factors are associated with non-alcoholic fatty liver disease, which is recognized as one of the predictors of cardiovascular diseases. Considering non-alcoholic fatty liver disease to be asymptomatic for a long time, it is very important to determine the relationships between various factors involved in the formation of pathology to early detect and prevent cardiovascular diseases in people of working age. Materials and methods. As part of a cross-sectional study, the prevalence of cardiovascular risk factors in metalworking workers was studied. The body mass index, lipid profile indicators, glucose, glycated hemoglobin, liver ultrasound results, lipid accumulation index, physical activity were analyzed. Results. The study revealed the presence of liver steatosis in 37% of the study participants. In 19%, liver steatosis was detected with a normal body mass index with a predominance in the “elderly” group; the values of the lipid profile are statistically significantly higher in the group of people diagnosed with liver steatosis: total cholesterol (p <0.001), triglycerides (p <0.001), atherogenicity index (p <0.001); and hyperglycemia (p <0.001). The coefficient of lipid accumulation increases with age, presence of steatosis, and obesity. In the group of persons with hepatic steatosis, persons with low physical activity significantly predominate. Limitations. The study has regional (Saratov region) and occupational (workers of the metalworking industry) limitations. Conclusion. The results of the study showed a high prevalence of liver steatosis among metalworking workers, mainly in elderly men. The established interrelations of the studied cardiovascular risk factors confirm significant cardiometabolic disorders in metalworking workers, which, under conditions of additional exposure to production factors, can potentiate the development of cardiovascular diseases and their complications, cause fatal cases, including at work.
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