Abstract
Objective: Introduction. According to the latest clinical research great attention to provide a study of the clinical conditions that contribute to increase the risk for cardiovascular complications. The combinations essential hypertension (EH) and mellitus diabetes (MD) causes the development of fatal and nonfatal cardiovascular events. Purpose. The aim of the study was to identify possible factors of MD in patients with EH the I-II stage with normoglycemia in a 15–20 year follow up. Design and method: Methods. We examined 54 patients with EH I-II st. Reexamined were conduct in the same conditions in 15–20 years. All patient divided in two groups: 1-st gr. (n = 39) – pts with only EH, 2-nd gr. (n = 15) – pts with comorbidy status (EH and diabetes). The frequency of development MD in our research consisted 27,8%. Results: Results. At the basing examine groups were same by age, gender, hemodynamics parameters and the structural data of the EhoCG. But initial body mass index (BMI) (kg/m2) were more higher (p < 0,013) in pts of 2-nd gr. (30,41 ± 0,44) than in pts of 1-st gr. (27,94 ± 0,44) and glycemia - (p < 0,002) in pts of 2-nd gr. - 5,93 ± 0,35 mmol/l and 4,61 ± 0,15 mmol/l in pts of 1-st gr. The results of re-examination (in 15–20 years) demonstrated reliable increase indicators between the 1-st and the 2-nd groups of BMI (0,21 ± 0,06 and 0,47 ± 0,11, p < 0,05), hemodynamics parameters: systolic blood pressure (BP) (−0,97 ± 4,06 and 33,46 ± 5,43, p < 0,0001), diastolic BP (−6,23 ± 2,67 and 6,77 ± 3,00, p < 0,027), and pulse BP (5,26 ± 2,33 and 26,69 ± 4,87, p < 0,0001). Conclusions: Conclusion. The results of this study showed that the following risk factors: the presence of initial obesity (BMI = 30,41 ± 0.44 kg/m2) with increasing normal blood glucose (5,93 ± 0.35 mmol/l), uncontrolled arterial (systolic, diastolic and pulse) hypertension associated with the risk of development of diabetes mellitus in patients with EH during a long period of time (in 15–20 years).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
