Abstract
Background Recently, personalized external aortic root support (PEARS) has been proposed as an alternative prophylactic surgery to prevent dilatation of the aortic root and dissection in Marfan syndrome patients. Briefly, a model of each patient’s aortic root and ascending aorta is created based on cardiac magnetic resonance (CMR) images. The model is then used to produce a bespoke external aortic root support made up of polymer mesh for each patient ready for surgical implantation[1]. The surgery is quicker than conventional aortic root replacement without the need for cardiopulmonary bypass or circulatory arrest. In addition, the blood endothelium interface is not interrupted and the native aortic valve is preserved obviating the need for life-long anticoagulation. Early positive result have been acknowledged in a recent NICE guidance document[2,3]. The aim of this study is to assess long term changes in aortic dimensions following PEARS surgery.
Highlights
Personalized external aortic root support (PEARS) has been proposed as an alternative prophylactic surgery to prevent dilatation of the aortic root and dissection in Marfan syndrome patients
The aortic root size was held stable without any significant increase in follow-up after personalized external aortic root support (PEARS) surgery (Figure 1)
This study demonstrates the long term effectiveness of PEARS surgery in preventing progressive aortic root dilatation in Marfan syndrome patients
Summary
Personalized external aortic root support (PEARS) has been proposed as an alternative prophylactic surgery to prevent dilatation of the aortic root and dissection in Marfan syndrome patients. Measurements immediately before surgery and at the latest follow-up were compared. All measurements were performed randomly and blinded
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