Abstract

Despite the high prevalence of hypertension (HTN), only a small proportion of the hypertensive patients will ultimately develop hypertensive crisis. In fact, some patients with hypertensive crisis do not report a history of HTN or previous use of antihypertensive medication. The majority of the patients with hypertensive crisis often report non-specific symptoms, whereas heart-related symptoms (dyspnea, chest pain, arrhythmias, and syncope) are less common. Hypertensive crises can be divided into hypertensive emergencies or hypertensive urgencies according to the presence or absence of acute target organ damage, respectively. This differentiation is an extremely useful classification in clinical practice since a different management is needed, which in turn has a significant effect on the morbidity and mortality of these patients. Therefore, it is very crucial for the physician in the emergency department to identify the hypertensive emergencies and to manage them through blood pressure lowering medications in order to avoid further target organ damage or deterioration. The aim of this narrative review is to summarize the recent evidence in an effort to improve the awareness, recognition, risk stratification, and treatment of hypertensive crisis in patients referred to the emergency department.

Highlights

  • Systemic hypertension (HTN) is the most common chronic medical disorder affecting over 1 billion people worldwide and more than 65 million adults in the Unites States [1]

  • Among the HTN population, about 1–2% of the patients will develop hypertensive crisis, which according to the 2003 Joint National Committee (JNC) on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) is defined as the elevation of systolic blood pressure (SBP) >179 mmHg or diastolic blood pressure (DBP) >109 mmHg [4]

  • Hypertensive crisis has the potential of end-organ damage, and this has a significant effect on patient’s prognosis

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Summary

INTRODUCTION

Systemic hypertension (HTN) is the most common chronic medical disorder affecting over 1 billion people worldwide and more than 65 million adults in the Unites States [1]. In hypertensive urgencies, the blood pressure (BP) should be reduced within 24–48 h, whereas hypertensive emergencies require immediate BP reduction in order to prevent irreversible target organ damage [2] Despite this distinction, a patient presenting with hypertensive urgency may have history of previous end-organ damage and chronic HTN without ongoing or imminent target organ dysfunction [2, 5]. The aim of this narrative review is to summarize the recent evidence in an effort to improve the awareness, recognition, risk stratification, and treatment of hypertensive crisis in patients referred to the emergency department

EPIDEMIOLOGY AND CLINICAL PROFILE
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